プログレッシブ和英中辞典(第３版)の解説
さしさわる【差し障る】
obstruct, hinder; 〔悪影響を与える〕adversely affect⇒さわる(障る)，さまたげる(妨げる)，さしつかえる(差し支える)
- 野党の野次が激しくて議事進行に差し障った
The proceedings were obstructed [hindered] by violent jeering from the Opposition benches. - めがねがないと細かい字を読むのに差し障る
Without glasses I have trouble (in) reading small letters. - それ以上飲むと明日の仕事に差し障るよ
If you drink any more, it'll 「interfere with [affect] your work tomorrow.